Pesquisa | SciELO

Resumen El almidón resistente (AR) es una fracción del almidón no digerible por las α-amilasas y a diferencia de la fibra dietética, el AR es fermentado en el colon promoviendo beneficios en la salud. Dentro de los diferentes tipos de AR, el tipo 3 (AR3) se obtiene por autoclaveado y sin el uso de agentes químicos. El objetivo de este estudio fue obtener AR3 a partir de avena y evaluar su efecto a diferentes concentraciones (0, 5, 10, 15 y 20 %, p/p) sobre las propiedades reológicas de la masa, propiedades de textura de las galletas y su aceptabilidad sensorial. El análisis de perfil de textura (TPA) evidenció un incremento en la fracturabilidad, dureza, adhesividad y gomosidad. La incorporación de AR3 incrementó el módulo elástico (G´) y viscoso (G´´) en comparación con la masa control. Todos los tratamientos presentaron comportamiento elástico (G´ > G´´). La dureza en las galletas aumentó con la concentración de AR3, con valores de ≈ 8 N (control) hasta 20 N (AR3-20 %). Las pruebas sensoriales no fueron significativas entre tratamientos, aunque las galletas AR3-20 % tuvieron mayor preferencia. La adición de AR3 en la masa provocó cambios funcionales y de textura significativos que afectaron positivamente los atributos de calidad de las galletas.

Abstract Resistant starch (RS) is a portion of starch that is not digestible by α-amylases and unlike dietary fiber, RS is fermented in the colon, promoting health benefits. Among the different types of RS, type 3 (RS3) is obtained by autoclaving and without chemical agents. The objective of this work was to obtain RS3 from oats and to evaluate its effect at different concentrations (0, 5, 10, 15 and 20 % w/w) on the rheological properties of the dough, textural properties of the cookies and their sensory acceptability. Texture profile analysis (TPA) showed an increased fracturability, hardness, adhesiveness and gumminess. The incorporation of RS3 increased the elastic (G’) and viscous (G’’) modulus compared to the control dough. All treatments showed elastic behavior (G’ > G’’). Hardness in cookies increased with RS3 concentration, with values from ≈ 8 N (control) to 20 N (RS3 - 20 %). Sensory tests were not significant between treatments, although RS3-20 % cookies had a higher preference. The addition of RS3 in the dough caused significant functional and textural changes that positively affected the quality attributes of the cookies.

https://doi.org/10.18633/biotecnia.v25i2.1854

Efectos del biocarbón obtenido a partir de residuos agrícolas de uva en la generación de biogás
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Diaz Vento, Ingrind

; Ancco, Midwar

; Peña Davila, Godofredo

; Ancco-Loza, Rodolfo

; Davila Del-Carpio, Gonzalo

; Jimenez Pacheco, Hugo Guillermo

Revista de Investigaciones Altoandinas

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Out 2022, Volume 24 Nº 4 Páginas 278 - 288

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract The wine industry produces a large amount of waste every year, this waste is generally not properly managed and becomes an environmental and sanitary hazard. On the other hand, the production of clean energies such as biogas from cattle manure has become an important energy resource. The aim of this study was to evaluate the biochar obtained by torrefaction of agricultural grape residues in the production and quality of biogas produced by anaerobic digestion of cattle manure. The study was carried out in the experimental area of the La Católica farm, located in Majes, Arequipa-Peru. A multiple factorial design composed of nine treatments was used to produce biochar, where the operating parameters were temperature and torrefaction time; and response parameters were grape residue mass yield, biogas yield and quality. The results indicate that temperature and torrefaction time significantly influence biochar production, with 40 min and 263.00°C being ideal values. Furthermore, biochar efficiently reduces the CO2 and H2S content up to 22% and 0.78 ppm, respectively, of the biogas. However, no impact on biogas and methane yields was observed. The use of waste to produce biochar and improve the quality of biogas can be replicated wherever the wine industry is developed, both in regions close to the coast and in mountainous regions of the Andean countries, achieving an integrated agroecological system, as it promotes sustainable agricultural practices, thus conserving biocultural resources.

Resumen La industria vitivinícola produce gran cantidad de residuos cada año, residuos que por lo general no son manejados adecuadamente y se convierten por ello en un riesgo ambiental y sanitario. De otra parte, la producción de energía limpia, como el biogás a partir de estiércol vacuno, se ha convertido en un recurso energético importante. El objetivo de este estudio fue evaluar el biocarbón obtenido por torrefacción de residuos agrícolas de uva en la producción y calidad de biogás producido por digestión anaerobia de estiércol vacuno. El estudio se realizó en el área experimental del fundo La Católica, ubicado en Majes, Arequipa, Perú. Se empleó un diseño factorial múltiple compuesto por nueve tratamientos para producir biocarbón, en el cual los parámetros operativos fueron la temperatura y el tiempo de torrefacción; y parámetros de respuesta fueron el rendimiento másico de residuos de uva, rendimiento y calidad del biogás. Los resultados indican que la temperatura y el tiempo de torrefacción influyen significativamente en la producción de biocarbón, y los valores ideales son 40 min y 263.00°C. Además, el biocarbón reduce eficientemente el contenido de CO2 y H2S hasta 22% y 0.78 ppm respectivamente, del biogás. No obstante, no se observó ningún impacto en los rendimientos de biogás y metano. El aprovechamiento de residuos para producir biocarbón y mejorar la calidad del biogás puede ser replicado en cualquier lugar donde se desarrolle la industria vitivinícola, tanto en regiones cercanas a la costa como en regiones montañosas de los países andinos, y se logra así un sistema agroecológico integral, ya que promueve prácticas agrícolas sostenibles al conservar los recursos bioculturales.

https://doi.org/10.18271/ria.2022.423

Two-year prevalence of spinal gunshot injuries in Mexico: A single center experience
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Villarreal-García, Francisco I.

; Martínez-Gutiérrez, Oscar A.

; Reyes-Fernández, Pedro M.

; Saavedra-Badillo, Luis A.

; Morales Avalos, Rodolfo

; Acosta-Olivo, Carlos A.

; Peña-Martínez, Víctor M.

Cirugía y cirujanos

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Ago 2022, Volume 90 Nº 4 Páginas 467 - 472

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Objective: The purpose of this study is to report epidemiological and clinical data of the patients that were admitted with spinal gunshot injuries. Methods: This was retrospective study and observational study. Patients who had a spinal injury secondary to a gunshot wound that was admitted to our hospital (level III trauma center) from July 2018 through July 2020 were included in the study. Demographic and clinical data including age, gender, civil status, occupation, level of injury (cervical, thoracic, or lumbar), degree of neurological impairment at admission, associated injuries, treatment established, length of hospital stay, and mortality rate were recorded. Results: A total of 55 patients were included in the study, of which 50 patients (90.9%) were men and five female patients (9.09%). The average age was 30.2 years. Three patients died during hospitalization representing a mortality rate of 5.45%. Conclusions: Spinal gunshot injuries are associated with significant sequelae, requiring long and costly treatments. This study obtained one of the highest incidences of gunshot injuries to the spine reported in the literature.

Resumen Objetivo: El propósito de este estudio es reportar datos epidemiológicos y clínicos de los pacientes que ingresaron con heridas por arma de fuego en columna. Métodos: Estudio retrospectivo y observacional. Se incluyeron pacientes que presentaban una lesión medular a secundaria a una herida por arma de fuego que ingresaron en nuestro hospital (centro de trauma de nivel III) desde julio de 2018 hasta julio de 2020. Se registraron datos demográficos y clínicos que incluían edad, sexo, estado civil, ocupación, grado de lesión (cervical, torácica o lumbar), grado de deterioro neurológico al ingreso, lesiones asociadas, tratamiento establecido, duración de la estancia hospitalaria y tasa de mortalidad. Resultados: Se incluyeron en el estudio un total de 55 pacientes, de los cuales 50 pacientes (90,9%) eran hombres y 5 mujeres (9,09%). La edad media fue de 30,2 años. Tres pacientes fallecieron durante la hospitalización lo que representa una tasa de mortalidad del 5,45%. Conclusiones: Las lesiones por arma de fuego en la columna están asociadas con secuelas importantes, que requieren tratamientos largos y costosos. Este estudio obtuvo una de las incidencias más altas de heridas por arma de fuego en la columna vertebral reportadas en la literatura.

https://doi.org/10.24875/ciru.21000011 30 downloads

EFFECT OF REACTION CONDITIONS ON PARTICLE SIZE OF ZNO NANOPARTICLES VIA CONTROLLED PRECIPITATION METHOD AND IN-VITRO ANTIBACTERIAL CAPACITY
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Toscano, Miguel A. Pedroza

; Peña, Rodolfo Salazar

; Velasco, Martín Rabelero

; Montalvo, José J. Ibarra

; Guzmán, Jesús A. Aréchiga

; Cuenca, Susana López

Química Nova

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Ago 2022, Volume 45 Nº 8 Páginas 901 - 905

Resumo: En | Texto: En | PDF: En

High-yield ZnO spheroidal nanoparticles with an average diameter around 23 nm (≈ 25% frequency) and 30 nm (≈ 28% frequency) were obtained by controlled semicontinuous precipitation at low temperatures. This synthesis was obtained from hydrozincite (Zn5(CO3)2(OH)6) as primary nanoparticles. The Zn5(CO3)2(OH)6 nanoparticles were synthesized by hydrolysis of Zn(NO3)2 in aqueous solution of (NH4)2CO3 and later, the precipitation becomes. Two temperatures of 60 and 70 °C in combination with three times of reaction were tested; followed by calcination of the precipitate at 400 °C. This range of sizes of nanoparticles is comparable with those obtained by other methods reported in the literature, such as microemulsions, however, here the advantage was not using solvents or surfactants. The ZnO nanoparticles were characterized by energy dispersive X-ray spectroscopy coupled to a scanning electron microscopy (SEM-EDS), transmission electronic microscopy (TEM), and X-ray diffraction. The antibacterial activity of the films against Gram-positive (S. aureus) and Gram-negative (E. coli.) bacteria was investigated using the disc diffusion method. The best results were found in the inhibition zone for Gram-positive bacteria, when the concentration of ZnO NPs incorporated was 3 mg disc-1.

https://doi.org/10.21577/0100-4042.20170881

Modelo de agentes inteligentes para simular el tránsito peatonal en ferias comerciales urbanas durante la pandemia del COVID-19
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Peña Zamalloa, Gonzalo Rodolfo

Revista de urbanismo

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Jun 2022, Nº 46 Páginas 22 - 39

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract: The COVID-19 pandemic highlighted the need for new approaches to the urban environment. Among them, physical distancing is intended to minimize contagion and safeguard general welfare. In the present research, a simulated model was designed to identify close contacts during pedestrian traffic in specific urban activities such as a trade fair. This research type was applied and of quasi-experimental design, a parametric simulation model based on intelligent agents was developed at the micro level in urban trade fair scenarios. Initially, theoretical trade fair configurations were compared, considering the shape of the walkable space and the arrangement of trade stands. Then, a manipulation of particular parameters is performed, among them, the probability of making a stall visible and the probability of stopping in case of direct contact or collision. Finally, the results were compared using statistical correlations, the PerMANOVA test, Games-Howell and the graphical analysis of the micro-simulated pedestrian behaviors by the developed model. It is concluded that the model is valid for theoretical pedestrian traffic models for the five simulated urban fairground scenarios.

Resumen: La pandemia del COVID-19 reveló la necesidad de contar con nuevas aproximaciones para el estudio del entorno urbano. Entre ellas, el distanciamiento físico, el cual tiene como propósito minimizar los contagios y salvaguardar el bienestar general. En la presente investigación, se diseñó un modelo simulado para identificar de contactos cercanos durante el tránsito peatonal en actividades urbanas específicas como la feria comercial. El tipo de investigación fue aplicada y de diseño cuasiexperimental, se desarrolló un modelo de simulación paramétrica basado en agentes inteligentes a nivel micro en escenarios urbanos feriales. Inicialmente, se compararon configuraciones de ferias comerciales teóricas, considerando la forma del espacio caminable y la disposición de puestos comerciales. Luego, se realizó una manipulación de parámetros particulares, entre ellos, la probabilidad de visibilizar un puesto y la probabilidad de detenerse ante un contacto directo o colisión. Finalmente, se contrastaron los resultados usando correlaciones estadísticas, la prueba de PerMANOVA, Games-Howell y el análisis gráfico de las conductas peatonales microsimuladas por el modelo desarrollado. Se concluye que el modelo es válido desde una perspectiva estocástica de estudio del tránsito peatonal para los cinco escenarios urbanos feriales simulados.

https://doi.org/10.5354/0717-5051.2022.63725 19 downloads

DINNP-U: A Design Process for Digital Innovation Platforms In Energy Sector Companies
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Canelón, Rodolfo

; Peña, Camilo

; Salazar, Andrés

Journal of technology management & innovation

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2022, Volume 17 Nº 3 Páginas 59 - 69

Resumo: En | Texto: En | PDF: En

Abstract This article proposes a process for digital innovation platforms in the energy sector called DINNPU. The research method involves the documentary review of research in the field of innovation, transformation, and digital platforms capable of generating value and innovation to its ecosystem. As a result, we generated a conceptual and theoretical basis that allowed the formalization of the disciplines for the design of digital innovation platforms. The process we propose can be used in the development of innovation platforms and can be instantiated for a specific domain. Moreover, the assets produced can be reused to generate a product from a family of domains. The main disciplines of this process are analysis, design, and implementation of digital platforms. For the case study, an interview was conducted with a group of specialists in the ICT area of an energy company (Utilities) in order to understand the digitization process or current maturity of this company. Then it was validated whether the proposed model or design is applicable or should wait until the company achieves the necessary digital maturity. The contribution of this study is to propose a process for domain engineering, which allows contributing with knowledge and experience, for digital innovation platforms in various industrial sectors. There is an interest in this phenomenon due to global trends such as digital transformation and industry 4.0.

DEVELOPMENT AND ASSESSMENT OF SPECTROSCOPY METHODOLOGIES AND CHEMOMETRICS STRATEGIES TO DETECT PHARMACEUTICALS BLEND ENDPOINT IN A PHARMACEUTICAL POWDER BLEND
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Pino-Torres, César

; Castillo-Felices, Rosario

; Mundaca-Uribe, Rodolfo

; Mendez-Herrera, Paola

; Aranda-Bustos, Mario

; Peña-Farfal, Carlos

Journal of the Chilean Chemical Society

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Dez 2021, Volume 66 Nº 4 Páginas 5387 - 5397

Resumo: En | Texto: En | PDF: En

ABSTRACT Manufacturing pharmaceutical products is one of the most regulated industrial processes due to the importance of its effects on human health. These processes require many physical and chemical determinations through chromatographic techniques coupled with different detectors. However, the pharmaceutical industry is not considering the growth that spectroscopic techniques have had in these fields of application, especially to monitor the blending process. This study evaluates different sampling methods for pharmaceutical blending processes by near-infrared spectroscopy (NIRS) and Vis-NIR spectroscopy. The pharmaceutical mixture consisted of three active ingredients at different concentrations. Various qualitative and quantitative strategies were used to evaluate the endpoint of the blending process. The results revealed the feasibility of different spectral analyses to establish the homogeneity of the mixture, which may be especially useful for applications at the industrial level in routine analysis or as a first choice. HPLC confirmed the final blend.

https://doi.org/10.4067/s0717-97072021000405387 23 downloads

CLASIFICACIÓN ESPACIAL DEL SUELO URBANO POR EL VALOR ESPECULATIVO DEL SUELO E IMÁGENES MSI SATELITALES USANDO K-MEANS, HUANCAYO, PERÚ
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Peña Zamalloa, Gonzalo Rodolfo

Urbano (Concepción)

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Nov 2021, Volume 24 Nº 44 Páginas 70 - 83

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT The city of Huancayo, like other intermediate cities in Latin America, faces problems of poorly planned land-use changes and a rapid dynamic of the urban land market. The scarce and outdated information on the urban territory impedes the adequate classification of urban areas, limiting the form of its intervention. The purpose of this research was the adoption of unassisted and mixed methods for the spatial classification of urban areas, considering the speculative land value, the proportion of urbanized land, and other geospatial variables. Among the data collection media, Multi-Spectral Imagery (MSI) from the Sentinel-2 satellite, the primary road system, and a sample of direct observation points, were used. The processed data were incorporated into georeferenced maps, to which urban limits and official slopes were added. During data processing, the K-Means algorithm was used, together with other machine learning and assisted judgment methods. As a result, an objective classification of urban areas was obtained, which differs from the existing planning.

RESUMEN La ciudad de Huancayo, como otras ciudades intermedias en Latinoamérica, enfrenta problemas de cambios de uso de suelo poco planificados y una acelerada dinámica del mercado del suelo urbano. La escases y desactualización de información sobre el territorio urbano impiden la adecuada clasificación de áreas urbanas, limitando la forma de su intervención. Esta investigación tuvo como objetivo la incorporación de métodos no asistidos y mixtos para la clasificación espacial de zonas urbanas considerando el valor especulativo del suelo, la proporción del suelo urbanizado y otras variables geoespaciales. Entre los medios de recolección de datos, se usó imágenes Multi-Espectrales (MSI) del satélite Sentinel-2, el sistema vial primario y una muestra de puntos de observación directa. Los datos procesados fueron incorporados en mapas georreferenciados, a los cuales se añadió además los límites urbanos y pendientes oficiales. Durante el procesamiento de los datos se empleó el algoritmo K-Means, junto a otros métodos de machine learning y juicio asistido. Como resultado, se obtuvo una caracterización objetiva de zonas urbanas que difiere de la planificación existente.

https://doi.org/10.22320/07183607.2021.24.44.06 92 downloads

Comparación de cuatro técnicas quirúrgicas para el manejo de la espondilitis tuberculosa de la columna torácica en adultos
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Martínez-Gutiérrez, Óscar A.

; Baena-Trejo, José E.

; Peña-Martínez, Víctor M.

; Reyes-Fernández, Pedro M.

; Zertuche-González, Elsa L.

; Villarreal-García, Francisco I.

; Morales-Avalos, Rodolfo

Cirugía y cirujanos

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Jun 2021, Volume 89 Nº 3 Páginas 295 - 302

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Objective: To compare the efficiency of the 4 most used surgical techniques for the management of tuberculous spondylitis. Method: Retrospective study in which adult patients with a confirmed diagnosis of tuberculous spondylitis, involvement of two vertebral levels or less, and without severe vertebral deformity were included. The medical records, imaging studies, and demographic data of the operated patients were collected and reviewed to retrospectively analyze the clinical results of each group. The primary variables were cure of infection, spinal fusion, and complications. The secondary variables included intraoperative bleeding, hospital stay, and surgical time. Results: There were no significant differences (p ≥ 0.05) in most of the variables analyzed, however, there were (p ≤ 0.001) regarding bleeding, surgical time, hospital stay and complications between the groups analyzed, with a lower result in all cases for the single posterior approach. Conclusions: The single posterior approach obtained a clinical efficacy similar to the rest of the approaches in terms of eradication of the infection and vertebral fusion, however, it was associated with less surgical invasion (surgical time and bleeding), a shorter hospital stay and complications.

Resumen Objetivo: Comparar la eficiencia de las cuatro técnicas quirúrgicas más utilizadas para el manejo de la espondilitis tuberculosa. Método: Estudio retrospectivo en el que se incluyeron pacientes adultos con diagnóstico confirmado de espondilitis tuberculosa, afectación de dos niveles vertebrales o menos y sin deformidad vertebral grave. Se recopilaron y revisaron los expedientes médicos, los estudios de imagen y los datos demográficos de los pacientes intervenidos para analizar retrospectivamente los resultados clínicos y funcionales de cada grupo. Las variables primarias fueron la erradicación de la infección, la fusión vertebral y las complicaciones. Entre las variables secundarias se estudiaron el sangrado intraoperatorio, la estancia hospitalaria y el tiempo quirúrgico. Resultados: Entre los grupos analizados no hubo diferencias significativas (p ≥ 0.05) en la mayoría de las variables analizadas, pero sí (p ≤ 0.001) respecto al sangrado, el tiempo quirúrgico, la estancia intrahospitalaria y las complicaciones, a favor del abordaje posterior único. Conclusiones: El abordaje posterior único logró una eficacia clínica similar a la del resto de los abordajes en términos de erradicación de la infección y fusión vertebral; sin embargo, se asoció a menores tiempo quirúrgico, sangrado, estancia hospitalaria y complicaciones.

https://doi.org/10.24875/ciru.20000907 9 downloads

10.

La inspección del lugar del hecho y la valoración legal de la huella o evidencia
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Fernández Romo, Rodolfo Máximo

; Peña Aguirre, Juan Antonio

; Huertas Díaz, Omar

Revista Logos Ciencia & Tecnología

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Dez 2020, Volume 12 Nº 3 Páginas 115 - 127

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN La inspección del lugar del hecho la concibe la criminalística como una acción táctica que se realiza siempre que sea posible a los efectos de obtener huellas o evidencias por las cuales se explique qué aconteció, así como identificar tanto a las víctimas como a los victimarios, con el fin de desplegar un proceso investigativo. El trabajo que se presenta tiene como objetivo demostrar cómo cuando esta operación investigativa se realiza cumpliendo las normas metodológicas de la criminalística, entre las que se incluye el respeto de la cadena de custodia, permite aportar huellas y evidencias a partir de las cuales se pueden emitir dictámenes periciales fundamentados con razón de ciencia. Estas evidencias alcanzan a ser valoradas por los jueces como parte de la prueba que se vierte en el proceso. En la elaboración del artículo se hizo uso de bibliografía especializada y de la experiencia de los autores como peritos, jueces y profesores universitarios. Como métodos del conocimiento se utilizó el análisis-síntesis y la inducción-deducción. Como principales resultados se exhibe la relación que existe entre una adecuada inspección del lugar del hecho, el análisis de la huella o evidencia en el laboratorio forense y la valoración del dictamen como elemento de prueba, lo que puede servir de referente a investigadores, peritos y operadores del sistema de justicia penal.

ABSTRACT The inspection of the crime scene is conceived by criminalistics as a tactical action that is carried out whenever possible in order to obtain traces or evidence in order to explain what happened, as well as to identify both the victims and the perpetrators, with the objective of deploy an investigative process. The research that is presented aims to demonstrate how when this investigative operation is carried out in compliance with the methodological norms of criminology, including respect for the chain of custody, it is possible to provide traces and other evidence from which expert opinions based on science can be issued. This evidence is evaluated by a judge and is part of the evidence that is given in a process. In preparing the article, use was made of specialized bibliographies and the experience of the authors as experts, judges and university professors. For knowledge methods, analysis-synthesis and induction-deduction were used. The main results are the relationship between an adequate inspection of the crime scene, the analysis of the traces or evidence in the forensic laboratory and the assessment of the expert opinion as evidence, which can serve as a reference for investigators, experts and operators of the criminal justice system.

RESUMO A inspeção do lugar dos fatos é conceituada pela criminalística como uma ação tática que se realiza sempre que seja possível aos efeitos de obter marcas ou evidências pelas quais se explique o acontecido, bem como identificar tanto as vítimas quanto os vitimizadores, com o fim de desenvolver um processo de investigação. O trabalho apresentado visa demonstrar como, quando esta operação investigativa se realiza com a adimplência das normas metodológicas da criminologia, entre as que se inclui o respeito da cadeia de custódia, permite proporcionar marcas e evidências a partir das quais é possível emitir parecer pericial fundamentado na ciência. Estas evidências serão analisadas pelos juí-zes como parte da prova apresentada no processo. Na elaboração do artigo fez-se uso da bibliografia especializada e da experiência dos autores como peritos, juízes e professores universitários. Como métodos do conhecimento utilizaram-se a análise-síntese e a indução-dedução. Como principais resultados se exibe a relação que existe entre uma adequada inspeção do lugar dos fatos, a análise do vestígio ou evidência no laboratório forense e a análise do parecer como elemento de prova, o que pode servir de referente a investigadores, peritos e operadores do sistema de justiça penal.

https://doi.org/10.22335/rlct.v12i3.1253 3312 downloads

11.

Intoxicación por paraquat vía parenteral
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Fuentes Mallozzi, Dante Alejandro

; Real Robles, Rodolfo del

; Peña Equihua, Mauricio

; Canizales Rivera, Juan Alberto

; Juárez Santiago, Carlos Avelino

Acta médica Grupo Ángeles

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Dez 2020, Volume 18 Nº 4 Páginas 411 - 413

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Herbicides are agricultural products widely distributed worldwide. Paraquat (1,1’-dimethyl-4,4’-bipyridyl) is a potent bipyridyl-type herbicide and desiccant, which is available as a 20% standard solution. In Mexico, it is still highly used despite attempts to restrict it. Due to its high lethality, it is used for suicide purposes. The main route of administration is the gastrointestinal route, although some cases have been reported intravenously, intramuscularly and intradermally. Parenteral paraquat poisoning is extremely rare and is associated in most cases with suicide attempt. We present the case of a 13-year-old female, who self-administered paraquat intramuscularly and who developed lethal complications as a consequence of intoxication by said product, whose death occurred 20 days after administration of paraquat.

Resumen Los herbicidas son productos agrícolas de amplia distribución mundial. El paraquat (1,1’-dimetil-4,4’-bipiridilo) es un potente herbicida y desecante de tipo bipiridilo, que se comercializa en forma de concentrado soluble al 20%. En México aún es altamente empleado, a pesar de intentos por restringirlo. Debido a su alta letalidad es utilizado con fines suicidas. La principal vía de uso es la gastrointestinal, aunque se han reportado algunos casos por vía intravenosa, intramuscular e intradérmica. La intoxicación por paraquat por vía parenteral es extremadamente rara y está asociada en la mayoría de los casos con intento de suicidio. Se presenta el caso de un femenino de 13 años de edad, quien se autoadministró paraquat por vía intramuscular y desarrolló complicaciones letales como consecuencia de la intoxicación por dicho producto, cuyo fallecimiento se produjo a los 20 días postadministración de paraquat.

https://doi.org/10.35366/97269 28 downloads

12.

Consenso colombiano de expertos sobre recomendaciones informadas en la evidencia para la prevención, el diagnóstico y el manejo de la infección por SARS-CoV-2/COVID-19 en pacientes con Enfermedad Renal Crónica en diálisis
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Yomayusa González, Nancy

; Yama, Erika

; González, Camilo

; Ariza, Amaury

; Aroca, Gustavo

; Baquero, Richard

; Rico, Jorge

; Vargas, Juan Guillermo

; Ramirez, Roberto

; Chacón, Kelly

; Robayo, Adriana

; Peña Wilches, Adalberto

; Meza, Adriana

; Bunch, Alfonso

; Mercado, Alvaro

; Calderón, Angélica

; Wancjer, Benjamín

; Zambrano, Betty

; Lozano, Carlos

; Buitrago, Cristóbal

; Ballesteros, David

; Chacón, Diana

; Vargas, Diana

; Villafañe, Douglas

; López, Francisco

; Pinzón, Freddy

; Guerrero, Gustavo

; Cárdenas, Héctor

; Benavides, Helman

; Villanueva, Ignacio

; Raoch, Ingrid

; Cáceres, Jimena

; Coronado, Jorge

; Pulido, Jorge

; Contreras, Kateir

; Valderrama Cometa, Luis Alfonso

; Gómez, María

; Vargas Brochero, María José

; Carrascal, Martha

; Rodríguez, Martha

; Guerrero, Mauricio

; Alfaro Tejeda, Mercedes

; Tobón, Natalia

; Rodríguez, Paula

; Gómez, Rafael

; Daza, Rodrigo

; Torres, Rodolfo

; Espitaleta, Zilac

; Burgos, Álvaro

Revista Colombiana de Nefrología

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Dez 2020, Volume 7 Supl. 2 Páginas 119 - 159

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Introducción: Las personas con diálisis de mantenimiento se consideran una población en alto riesgo de infección por SARS-CoV-2, complicaciones y muerte. La periodicidad de la diálisis, la organización y la demanda en las unidades de diálisis y las limitaciones de alfabetización en salud poblacional limitan el cumplimiento del aislamiento y el distanciamiento social. Objetivo: Desarrollar, mediante un consenso de expertos, recomendaciones informadas en evidencia para la prevención, el diagnóstico y el manejo de la infección por SARS-CoV-2/COVID-19 en pacientes con enfermedad renal crónica. Materiales y métodos: Se realizó una revisión rápida de literatura en Pubmed, Embase y sociedades científicas. La calidad de evidencia fue evaluada según el tipo de estudio incluido. El acuerdo se definió para cada recomendación con umbral de al menos 70% de aprobación. La fuerza de las recomendaciones fue graduada como fuerte o débil. Resultados: El colectivo fue consultado entre el 17 y 19 de mayo de 2020. Se obtuvo respuesta de 44 expertos clínicos que declararon conflicto de interés previo a la consulta. El acuerdo de las recomendaciones estuvo entre 70,5 y 100%. Se presentan las recomendaciones de un colectivo experto para la prevención, el diagnóstico y el manejo de infección por SARS-CoV-2/COVID-19 en pacientes con enfermedad renal crónica. Conclusión: Debido a la reciente aparición de la infección por SARS-CoV-2 y las incertidumbres respecto a la prevención, el diagnóstico y el manejo, las recomendaciones presentadas se conciben como un estándar colombiano que permita garantizar un cuidado centrado en las personas con enfermedad renal crónica y la protección de los profesionales de la salud.

Abstract Introduction: People with chronic dialysis are considered a population at high risk of SARS CoV2 infection and its derived complications and death. The need to go to strict dialysis schedules, the high demand in the kidney facilities and the difficulties derived from the time and space organization in the rooms in the face to the pandemic added to the difficult learning, teaching and adapting new protocols manifest the needed of standard recommendation according to this problem in people who couldn't have an ideal isolation. Objective: Develop through an expert consensus, evidence-informed recommendations for the prevention, diagnosis, and management of SARS-CoV-2/COVID-19 infection in patients with chronic kidney disease on Dialysis. Materials and methods: We carried out a quick literature review, PubMed, Embase and scientific societies were consulted. The quality of the evidence was considered according to the type of study included. The agreement threshold defined for each recommendation was > 70% approval among experts. The strength of the recommendations was rated as strong or weak. Results: Between May 17 and 19, 2020, was conformed a team of 44 clinical experts who declared their interest conflict prior to the consultation. The agreement of the recommendations was between 70.5% and 100%. The recommendations were separated in prevention, early identification, and diagnostic, isolation in hemodialysis facilities and peritoneal dialysis, and team protection. Ethical considerations also were included. Conclusion: Due to the recent appearance of SARS-CoV-2 infection and the uncertainties regarding prevention, diagnosis and management, the recommendations presented are conceived as a Colombian standard that allows guaranteeing focused care for people with chronic kidney disease and the protection of health team.

https://doi.org/10.22265/acnef.7.supl.2.474 347 downloads

13.

Consenso colombiano de expertos sobre recomendaciones informadas en la evidencia para la prevención, el diagnóstico y el manejo de la lesión renal aguda por SARS-CoV-2/COVID-19
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González, Camilo

; Yama, Erika

; Yomayusa, Nancy

; Vargas, Juan

; Rico, Jorge

; Ariza, Amaury

; Aroca, Gustavo

; Baquero, Richard

; Ramírez, Roberto

; Chacón, Kelly

; Torres, Rodolfo

; Robayo, Adriana

; Peña, Adalberto

; Meza, Adriana

; Molano, Alejandra

; Lizarazo, Alexandra

; Caicedo, Andrea

; Acevedo, Andrés

; Calderón, Angélica

; Zambrano, Betty

; Musso, Carlos Guido

; Lozano, Carlos

; Buitrago, Cristóbal

; Ballesteros, David

; Chacón, Diana

; Vargas, Diana

; Gayón, Diana

; Villafañe, Douglas

; López, Francisco

; Ardila, Freddy

; Pinzón, Guillermo

; Guerrero, Gustavo

; Benavides, Helman

; Villanueva, Ignacio

; Raoch, Ingrid

; Galeano, Javier

; Gordon, Jennifer

; Cáceres, Jimena

; Pulido, Jorge

; Pérez, Jorge

; Contreras, Kateir

; Aristizábal, Leidy

; Valderrama, Luis

; Gómez, María

; Vargas, María José

; Carrascal, Martha

; Rodríguez, Martha

; Guerrero, Mauricio

; Alfaro, Mercedes

; Tobón, Natalia

; García, Paola

; Rodríguez, Paula

; Daza, Rodrigo

; Espitaleta, Zilac

Revista Colombiana de Nefrología

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Dez 2020, Volume 7 Supl. 2 Páginas 89 - 117

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

resumen está disponible en el texto completo

Abstract Introduction: Acute kidney injury is a frequent complication in patients with COVID-19 and its occurrence is a potential indicator of multi-organ dysfunction and disease severity. Objective: Develop, through an expert consensus, evidence-based recommendations for the prevention, diagnosis, and management of acute kidney injury in patients with SARS CoV2 / COVID-19 infection. Materials and methods: Based on a rapid systematic review in Embase and Pubmed databases and documents from scientific societies, we made preliminary recommendations and consulted with an expert group through an online tool. Then we defined agreement after at least 70 % consensus approval. Quality evidence was evaluated according to the type of document included. The strength of the recommendations was graded as strong or weak. Results: Fifty clinical experts declared their conflict of interest; the consultation took place between May 2 and 29, 2020. The range of agreement ranged from 75.5 % to 100 %. Recommendations for prevention, diagnosis and management of acute kidney injury in patients with SARS CoV2 infection are presented. Conclusions: Although the good quality information available regarding acute kidney injury in patients with COVID-19 is scarce, the recommendations of clinical experts will guide clinical decision-making and strategies around patients with this complication, guaranteeing care focused on the people, with high quality standards, and the generation of safety, health and wellness policies for multidisciplinary care teams.

https://doi.org/10.22265/acnef.7.supl.2.73 434 downloads

14.

DETERMINATION OF ANTIOXIDANT CAPACITY (ORAC) OF GREIGIA SPHACELATA AND CORRELATION WITH VOLTAMMETRIC METHODS
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Aravena-Sanhueza, Felipe

; Pérez-Rivera, Mónica

; Castillo-Felices, Rosario

; Mundaca-Uribe, Rodolfo

; Aranda Bustos, Mario

; Peña Farfal, Carlos

Journal of the Chilean Chemical Society

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Set 2020, Volume 65 Nº 3 Páginas 4925 - 4928

Resumo: En | Texto: En | PDF: En

ABSTRACT The study and determination of the antioxidant capacity of the Greigia Sphacelata fruit were carried out. G. sphacelata is an endemic fruit of central-southern Chile, better known as Chupón or Quiscal. Spectrophotometric and modified ORAC test were developed for antioxidant capacity determinations, and later an electrochemical method was developed by differential impulse voltammetry (DPV) with a vitreous carbon electrode for the quantification of the antioxidant capacity expressed in equivalent of the Trolox standard in µmolL-1. Once the voltammetric test was developed, the correlation study between both methods used to determine the antioxidant capacity of Greigia sphacelata was carried out. The results of the determination of the antioxidant capacity of Greigia sphacelata by ORAC test report an antioxidant capacity of 3525 µmol/100gequivalents of Trolox. Concerning the concentration obtained by the electrochemical methodology, 724 µmol/100g Trolox equivalents is obtained for a linear correlation r = 0.969 with the spectrophotometric method.

https://doi.org/10.4067/s0717-97072020000204925 519 downloads

15.

High-throughput sequencing of the 16S rRNA gene to analyze the gut microbiome in juvenile and adult tropical gar (Atractosteus tropicus)
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Méndez-Pérez, Roberto

; García-López, Rodrigo

; Bautista-López, J. Santiago

; Vázquez-Castellanos, Jorge

; Alvarez-González, Carlos

; Peña-Marín, Emyr

; Baltierra-Trejo, Eduardo

; Adams-Schroeder, Randy

; Domínguez-Rodríguez, Verónica

; Melgar-Valdés, Carolina

; Martínez-García, Rafael

; Moya, Andrés

; Gómez-Cruz, Rodolfo

Latin american journal of aquatic research

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Jul 2020, Volume 48 Nº 3 Páginas 456 - 479

Resumo: En | Texto: En | PDF: En

ABSTRACT Tropical gar (Atractosteus tropicus) is freshwater and estuarine fish, inhabiting the Earth since the Mesozoic era and undergoing limited physiological variation ever since. Besides its recognized cultural and scientific relevance, the species has seen remarkable growth in its economic impact due to pisciculture. In this study, we present the first report of the whole taxonomic composition of microbial communities in gut contents in juveniles and adults of A. tropicus, by sex and origin (wild and cultivated). For this study, 508 genera were identified, with the most and least abundant being Cetobacterium and Paludibacter, respectively. Fusobacteria, Proteobacteria, Firmicutes, and Bacteroidetes phyla are the core gut microbiome of A. tropicus juvenile and adult by sex and origin. Deinococcus-Thermus phylum sequence was only identified in wild-type males. In the phylogenetic trees reconstruction Lactococcus lactis strains CAU929 and CAU6600, Cp6 and CAU9951, Cetobacterium strain H69, Aeromonas hydrophila strain P5 and WR-5-3-2, Aeromonas sobria strain CP DC28 and Aeromonas hydrophila were identified, some of them with probiotic potential within the three dominant phyla in core gut microbiome in A. tropicus adults, especially in wild-type organisms. Myroides genus was recognized in microbiota gut of the cultivated juvenile A. tropicus. Nevertheless, Alpha diversity indicated that the highest gut microbiota abundance and richness is found in cultivated juvenile and wild-type adult A. tropicus female, rather than adult wild-type males and the least gut microbiota abundance and richness is found in a cultivated adult of A. tropicus for both sexes.

https://doi.org/10.3856/vol48-issue3-fulltext-2419 974 downloads

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